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Molecular classification of non-small-cell lung cancer: diagnosis, individualized treatment, and prognosis

Yue Yu, Jie He

Frontiers of Medicine 2013, Volume 7, Issue 2, Pages 157-171 doi: 10.1007/s11684-013-0272-4

Abstract: Molecular biology techniques, particularly gene expression microarrays, proteomics, and next-generationsequencing, have recently been developed to facilitate effectively its molecular classification.The underlying etiology, pathogenesis, therapeutics, and prognosis of NSCLC based on an improved molecularThis review focuses on the molecular classification of NSCLC based on gene expression microarray technologyreported during the past decade, as well as their applications for improving the diagnosis, staging

Keywords： non-small-cell lung cancer molecular typing individualized medicine molecular-targeted therapy gene expression

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Research and application on high-end equipment of biological detection and molecular diagnosis

Peng Niancai,Li Lei,Li Zheng,Miao Baogang,Li Ming,Zhao Yao,Jiang Zhuangde

Strategic Study of CAE 2013, Volume 15, Issue 1, Pages 57-62

Abstract:

Based on biological detection and molecular diagnostics technology development, the author summarizeddisease control, food safety, quarantine inspection, biology and medical research field of molecularreal-time fluorescence quantitative polymerase chain reaction (PCR) nucleic acid detector, diagnosis

Keywords： biological detection molecular diagnosis real-time quantitative PCR ATP luminescence detection

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Laboratory diagnosis for malaria in the elimination phase in China: efforts and challenges

Frontiers of Medicine 2022, Volume 16, Issue 1, Pages 10-16 doi: 10.1007/s11684-021-0889-7

Abstract: The prompt and precise diagnosis of symptomatic and asymptomatic carriers of Plasmodium parasitesof the China Malaria Elimination Action Plan in 2010, China has formulated clear goals for malaria diagnosisVarious external quality assessments were implemented, and a national malaria diagnosis reference laboratorynetwork was established to strengthen the quality assurance in malaria diagnosis.This review summarizes the lessons about malaria diagnosis in the elimination phase, primarily including

Keywords： malaria laboratory diagnosis quality control malaria elimination China

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Special issue on “Molecular Sensors and Molecular Logic Gates”

Luling Wu , Tony D. James

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 1, Pages 1-3 doi: 10.1007/s11705-021-2134-y

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Design of bio-oil additives via molecular signature descriptors using a multi-stage computer-aided molecular

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 2, Pages 168-182 doi: 10.1007/s11705-021-2056-8

Abstract: In this work, computer-aided molecular design tools were developed to design optimal solvents to upgradeAs different property prediction models consist different levels of structural information, molecularDue to the combinatorial nature of higher-order signatures, the complexity of a computer-aided molecular

Keywords： computer-aided molecular design bio-oil additives molecular signature descriptor

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Progress on molecular biomarkers and classification of malignant gliomas

Chuanbao Zhang, Zhaoshi Bao, Wei Zhang, Tao Jiang

Frontiers of Medicine 2013, Volume 7, Issue 2, Pages 150-156 doi: 10.1007/s11684-013-0267-1

Abstract: reported over the last few decades, and these markers have made great contributions to the accuracy of diagnosisGreat efforts have been made to incorporate new information about the molecular landscape of gliomas

Keywords： malignant glioma molecular biomarker IDH1 MGMT molecular classification

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Molecular classification and molecular targeted therapy of cancer

Miao Xu, Jianyong Shao, Yixin Zeng

Frontiers of Medicine 2013, Volume 7, Issue 2, Pages 147-149 doi: 10.1007/s11684-013-0274-2

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Biosensor-based assay of exosome biomarker for early diagnosis of cancer

Frontiers of Medicine 2022, Volume 16, Issue 2, Pages 157-175 doi: 10.1007/s11684-021-0884-z

Abstract: Therefore, early diagnosis of cancer is indispensable in the timely prevention and effective treatmentExosome has recently become an attractive cancer biomarker in noninvasive early diagnosis because ofsensitivity, and remarkable specificity, suggesting promising biomedical applications in the early diagnosisregarding the assay of exosomes were summarized, and the superiorities of exosomes as markers for the early diagnosisMoreover, the recent challenges and further opportunities of developing effective biosensors for the early diagnosis

Keywords： biosensor exosome cancer diagnosis

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Tomographic diagnosis of defects in hydraulic concrete structure

ZHAO Mingjie, XU Xibin

Frontiers of Structural and Civil Engineering 2008, Volume 2, Issue 3, Pages 226-232 doi: 10.1007/s11709-008-0027-5

Abstract: The experimental results indicate that the result of the tomographic diagnosis of a single defect isDefects with the orientation perpendicular to the direction of the diagnosis may have higher precision

Keywords： satisfactory processing orientation tomographic diagnosis orientation perpendicular

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convolutional tree-inspired network: a decision-tree-structured neural network for hierarchical fault diagnosis

Frontiers of Mechanical Engineering 2021, Volume 16, Issue 4, Pages 814-828 doi: 10.1007/s11465-021-0650-6

Abstract: The fault diagnosis of bearings is crucial in ensuring the reliability of rotating machinery.However, the inexplicability and low generalization ability of fault diagnosis models still bar themneural network, that is, the deep convolutional tree-inspired network (DCTN), for the hierarchical fault diagnosisadvantages in 1) the hierarchical structure that can support more accuracy and comprehensive fault diagnosisThe multiclass fault diagnosis case and cross-severity fault diagnosis case are executed on a multicondition

Keywords： bearing cross-severity fault diagnosis hierarchical fault diagnosis convolutional neural network

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Method for solving the nonlinear inverse problem in gas face seal diagnosis based on surrogate models

Frontiers of Mechanical Engineering 2022, Volume 17, Issue 3, doi: 10.1007/s11465-022-0689-z

Abstract: However, they have not been introduced into gas face seal diagnosis tasks because of the unacceptable

Keywords： surrogate model gas face seal fault diagnosis nonlinear dynamics tribology

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Machine learning for fault diagnosis of high-speed train traction systems: A review

Frontiers of Engineering Management doi: 10.1007/s42524-023-0256-2

Abstract: Therefore, performing fault monitoring and diagnosis on the traction system of the HST is necessary.Machine learning has made considerably advancements in traction system fault diagnosis; however, a comprehensiveaims to review the research and application of machine learning in the field of traction system fault diagnosisThen, the research and application of machine learning in traction system fault diagnosis are comprehensivelyFinally, the challenges for accurate fault diagnosis under actual operating conditions are revealed,

Keywords： high-speed train traction systems machine learning fault diagnosis

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Pathogenesis, diagnosis, and treatment of recurrent spontaneous abortion with immune type

Qi-De LIN, Li-Hua QIU

Frontiers of Medicine 2010, Volume 4, Issue 3, Pages 275-279 doi: 10.1007/s11684-010-0101-y

Abstract: In the investigations of immunopathogenesis, diagnosis, and treatment of RSA since the late 1980s, itSystemic etiological screening process and diagnosis systems of RSA with immune type were developed,and anticardiolipin (ACL or ACA) + anti-β2-GP1 antibody combining multiple assays for effective diagnosisThe research achievement leads to great progress in the diagnosis and treatment of RSA in China.

Keywords： spontaneous abortion recurrent autoimmune alloimmune pathogenesis diagnosis immunotherapy

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Advances in Molecular Electronics: A Brief Review Review

Paven Thomas Mathew, Fengzhou Fang

Engineering 2018, Volume 4, Issue 6, Pages 760-771 doi: 10.1016/j.eng.2018.11.001

Abstract:

The field of molecular electronics, also known as moletronics, deals with the assembly of molecularNovel research has been performed in developing electrical-equivalent molecular components.Since there is a need to reduce the size of the silicon chip, attaining such technology at the molecularAlthough the experimental verification and modeling of molecular devices present a daunting task, vitalThis article combines an overview of various molecular components, such as molecular transistors, diodes

Keywords： Moletronics Molecular transistor Molecular diode Molecular capacitor Molecular wire Graphene

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Intelligent diagnosis methods for plant machinery

Huaqing WANG, Peng CHEN, Shuming WANG,

Frontiers of Mechanical Engineering 2010, Volume 5, Issue 1, Pages 118-124 doi: 10.1007/s11465-009-0084-z

Abstract: approaches based on artificial neural network and fuzzy algorithm for plant machinery, such as the diagnosismethod using the wavelet transform, rough sets, and fuzzy neural network; the diagnosis method basedon the sequential inference and fuzzy neural network; the diagnosis approach by the possibility theoryand certainty factor model; and the diagnosis method on the basis of the adaptive filtering techniqueThese intelligent diagnostic methods have been successfully applied to condition diagnosis in different

Keywords： intelligent diagnosis neural network fuzzy algorithm adaptive filtering plant machinery